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Ammonium Chloride and Pregnancy: Is it Safe?

Use

Ammonium chloride is used as:

  • An expectorant (to loosen mucus in coughs)
  • A urinary acidifier
  • A component in intravenous solutions (rare)

Risks in Pregnancy

  • No well-controlled studies in pregnant women
  • In high doses, it may cause:
    • Metabolic acidosis
    • Electrolyte imbalance
    • Risk of fetal distress due to acid-base imbalance
  • Animal studies are limited and inconclusive

🧪 FDA Pregnancy Category

Ammonium chloride is not assigned a formal FDA pregnancy category, but caution is advised.

👶 Recommendation

  • Use only if clearly needed and the benefits outweigh the risks
  • Avoid self-medication
  • Discuss with your doctor or pharmacist before use

📌 Summary

CriteriaStatus
Safe for self-use in pregnancy❌ Not recommended
Can be prescribed✅ With medical supervision
Known fetal harm⚠️ Possible with high doses or long use
Safer alternatives✅ Yes — e.g., saline, steam inhalation for coughs